Oncofinder

The OncoFinder (http://www.oncofinder.com/) is as an integrated system aiding in research and diagnostics in personalized oncology. It includes a comprehensive annotated database of the many targeted drugs that are already approved, undergoing clinical trials or are on the preclinical stage.

Publications about OncoFinder:

1. Buzdin AA, Zhavoronkov AA, Korzinkin MB, Venkova LS, Zenin AA, Smirnov PY, Borisov NM. (2014) Oncofinder, a new method for the analysis of intracellular signaling pathway activation using transcriptomic data. Front Genet. Mar 25; 5:55. doi: 10.3389/fgene.2014.00055. eCollection 2014.

http://journal.frontiersin.org/JOURNAL/10.3389/FGENE.2014.00055/FULL

2. Moskalev AA, Aliper AM, Smit-McBride Z, Buzdin A, Zhavoronkov A. (2014) Genetics and epigenetics of aging and longevity. Cell Cycle. 2014 Apr 1; 13(7):1063-77. doi: 10.4161/cc.28433.

http://www.tandfonline.com/doi/pdf/10.4161/cc.28433

3. Zhavoronkov A, Buzdin AA, Garazha AV, Borisov NM, Moskalev AA. (2014) Signaling pathway cloud regulation for in silico screening and ranking of the potential geroprotective drugs. Front Genet. 2014 Mar 3;5:49. doi: 10.3389/fgene. 2014.00049.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940060/pdf/fgene-05-00049.pdf

4. Borisov NM, Terekhanova NV, Aliper AM, Venkova LS, Smirnov PY, Roumiantsev S, Korzinkin MB, Zhavoronkov AA, Buzdin AA. (2014) Signaling pathway activation profiles make better markers of cancer than expression of individual genes. Oncotarget. 2014 Aug 23. pii: 2358. [Epub ahead of print] PubMed PMID: 25337906.

http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=2358

5. Aliper AM, Frieden-Korovkina VP, Buzdin A, Roumiantsev SA, Zhavoronkov A. (2014) Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer. Oncotarget. 2014 Sep 16. [Epub ahead of print] PubMed PMID: 25294811.

http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=2489

6. Lezhnina K, Kovalchuk O, Zhavoronkov AA, Korzinkin MB, Zabolotneva AA, Shegay PV, Sokov DG, Gaifullin NM, Rusakov IG, Aliper AM, Roumiantsev SA, Alekseev BY, Borisov NM, Buzdin AA. (2014) Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways. Oncotarget. 2014 Oct 15;5(19):9022-32. PubMed PMID: 25296972.

http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=2493