Our publications

 

Olga Kovalchuk:
2014
1. L. Luzhna, K. Kutanzi, O. Kovalchuk. Gene expression and epigenetic profile of mammary gland tissues of four different rat strains reveals the possible mechanisms of their differential predisposition to breast cancer. Mutation Research – Genetic Toxicology and Environmental Mutagenesis (in press).
2. I. Kovalchuk, A. Golubov, I. Koturbash, K. Kutanzi, O. Martin, O. Kovalchuk. Age-dependent changes in DNA repair in radiation-exposed mice. Radiation Research (in press).
3. C. Sidler, R. Woycicki, D. Li, B. Wang, I. Kovalchuk, O. Kovalchuk. A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts. Aging 6:545-63.
4. C. Sidler, R. Woycicki, I. Kovalchuk, O. Kovalchuk. WI-38 senescence is associated with global and site-specific hypomethylation. Aging 6: 564-74.
5. B. Wang, D. Li, A. Kovalchuk, D. Litvinov, O. Kovalchuk. Ionizing radiation-inducible miR-27b suppresses leukemia proliferation via targeting cyclin A2. International Journal of Radiation Oncology*Biology*Physics 90:53-62.
6. F.C.R. Zucchi, Y. Yao, Y. Ilnytskyy, J.C. Robbins, N. Soltanpour, I. Kovalchuk, O. Kovalchuk, G.A. Metz (2014) Lifetime Stress Cumulatively Programs Brain Transcriptome and Impedes Stroke Recovery: Benefit of Sensory Stimulation. PLoS ONE, 9(3):e92130.
7. O. Kovalchuk, P. Walz, and I. Kovalchuk. (2014) Does bacterial infection cause genome instability and cancer in the host cell? Mutat Res, 761: 1-14.
2013
8. C. Sidler, R.Woycicki, Y. Ilnytskyy, G.Metz, I.Kovalchuk, O. Kovalchuk. Immunosenescence Is Associated With Altered Gene Expression And Epigenetic Regulation In Primary And Secondary Immune Organs. Front. Genet. 4, 211
9. A. Zabolotneva, A.A Zhavoronkov, P.V. Shegay, N.M. Gaifullin, B.Y. Alekseev, S.A. Roumiantsev, A.V Garazha, O. Kovalchuk, A. Aravin, A. A. Buzdin. A systematic experimental evaluation of microRNA markers of human bladder cancer. Front. Genet. 4: 247
10. D. Li, Y. Ilnytskyy, A. Kovalchuk, L.M. Khachigian, R.T. Bronson, B. Wang, O. Kovalchuk. Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer. Oncotarget 4:1373-87.
11. L.V. Titova, A.K. Ayesheshim, A. Golubov, R. Rodriguez-Juarez, R. Woycicki, F.A. Hegmann, O. Kovalchuk. Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? Sci Rep. 3: 2363. doi: 10.1038/srep02363.
12. A. Kovalchuk, F. Aladedunye, R. Rodriguez-Juarez, D. Li, J. Thomas, O. Kovalchuk, R. Przybylski. Novel antioxidants are not toxic to normal tissues but effectively kill cancer cells. Cancer Biol Ther. 14: 907-15
13. I. Kovalchuk, P. Walz, J. Thomas, O. Kovalchuk. Genomic instability in liver cells caused by an LPS-induced bystander-like effect. PLoS One. 8(7):e67342. doi: 10.1371/journal.pone.0067342
14. L. Luzhna, P. Kathiria, O. Kovalchuk. Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond. Front Genet. 4:131. doi: 10.3389/fgene.2013.00131
15. L.V. Titova, A.K. Ayesheshim, A. Golubov, R. Rodriguez-Juarez, A. Kovalchuk, F.A. Hegmann, O. Kovalchuk. Intense picosecond THz pulses alter gene expression in human skin tissue in vivo. Proc SPIE: 8585
16. I. Kovalchuk, P. Walz, J. Thomas, O. Kovalchuk. The increased expression of proteins involved in proliferation, DNA repair and DNA methylation in spleen of mice exposed to E. coli O157:H7 lipopolysaccharide. Environ Mol Mutagen. 54: 421-8
17. K. Kutanzi, O.Kovalchuk. Exposure to estrogen and ionizing radiation causes epigenetic dysregulation, activation of mitogen-activated protein kinase pathways, and genome instability in the mammary gland of ACI rats. Cancer Biol Ther. 14:564-73
18. B. Wang, D. Li, O.Kovalchuk. p53 Ser15 phosphorylation and histone modifications contribute to IR-induced miR-34a transcription in mammary epithelial cells. Cell Cycle 12:2073-83.
19. C. Kirkby, E. Ghasroddashti, A. Kovalchuk, B .Kolb, O. Kovalchuk. Monte Carlo-based dose reconstruction in a rat model for scattered ionizing radiation investigations. Int J Radiat Biol. 89:741-9.
20. L.V. Titova, A.K. Ayesheshim, A. Golubov, D. Fogen, R. Rodriguez-Juarez, F.A. Hegmann, O. Kovalchuk. Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue. Biomed Opt Express. 4:559-68
21. M. Merrifield, O. Kovalchuk. Epigenetics in radiation biology: a new research frontier. Front Genet. 4:40. doi: 10.3389/fgene.2013.00040
22. L. Luzhna, A. Golubov, S. Ilnytskyy, V.F. Chekhun, O. Kovalchuk. Molecular mechanisms of radiation resistance in doxorubicin-resistant breast adenocarcinoma cells. Int J Oncol. 42:1692-708.
23. F.C. Zucchi, Y. Yao, I.D. Ward, Y. Ilnytskyy, D.M. Olson, K. Benzies, I. Kovalchuk, O. Kovalchuk, G.A. Metz. Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring. PLoS One. 8(2):e56967. doi: 10.1371/journal.pone.0056967
24. M.W. Koch, L.M. Metz, O. Kovalchuk. Epigenetic changes in patients with multiple sclerosis. Nat Rev Neurol. 9:35-43.
25. M.W. Koch, L.M. Metz, O. Kovalchuk. Epigenetics and miRNAs in the diagnosis and treatment of multiple sclerosis. Trends Mol Med. 19:23-30
2012
26. A. Kovalchuk, R. Rodriguez-Juarez, A. Muhammad, B. Kolb, O. Kovalchuk. Epigenetic bystander-like effects of stroke in somatic organs. Aging, 4: 224-34
27. R. Mychasiuk, S. Zahir, N. Schmold, S. Ilnytskyy, O. Kovalchuk, R. Gibb. Parental enrichment and offspring development: Modifications to brain, behavior and the epigenome. Behav Brain Res. 228: 294-8
2011
28. R. Mychasiuk, N. Schmold, S. Ilnystkyy, O. Kovalchuk, B. Kolb, and R. Gibb. Prenatal bystander stress alters brain, behavior, recovery from injury, and the epigenome of developing rat offspring. Dev Neurosci. 33(2):159-69
29. J.S.Dickey, F.J. Zemp, O.A. Martin, O. Kovalchuk. The role of miRNA in the direct and indirect effects of ionizing radiation. Radiat Environ Biophys. 50:491-9
30. Y. Ilnytskyy, O. Kovalchuk. Non-targeted radiation effects-An epigenetic connection. Mutat Res. 714:113-25
31. D. Hudson, I. Kovalchuk, I. Koturbash, B. Kolb, O.A. Martin, O. Kovalchuk. Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals. Aging (Albany NY). 3:609-20
32. S.I. Shpyleva, V.P. Tryndyak, O. Kovalchuk, A. Starlard-Davenport, V.F. Chekhun, F.A. Beland, I.P. Pogribny. Role of ferritin alterations in human breast cancer cells. Breast Cancer Res Treat., 2011 126:63-71
33. J. Tamminga and O. Kovalchuk. Role of epigenetic DNA methylation changes and DNA damage in radiation-induced bystander effects and genomic instability in germline in vivo. Current Molecular Pharmacology, 4:115-25.
34. J.S. Dickey, F.J. Zemp, A. Altamirano, O.A. Sedelnikova, W.M. Bonner, and O. Kovalchuk, H2AX phosphorylation in response to DNA double-strand break formation during bystander signalling: effect of microRNA knockdown. Radiat Prot Dosimetry 143: 264-9.
35. I. Koturbash, F. Zemp, B. Kolb and O. Kovalchuk. Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal lobe in a mouse model. Mutation Res., 722:114-8.
36. I. Koturbash, F. J. Zemp, I. Pogribny and O. Kovalchuk. Small molecules with big effects: The role of the microRNAome in cancer and carcinogenesis. Mutation Res., 722:94-105.
2010
37. K.L. Witt, P.G. Moorman, O. Kovalchuk, N. Holland, G. Block, P.R. Andreassen. Genetics and women’s health issues-The commitment of EMS to women scientists and gender-associated disease topics. Environ Mol Mutagen, 51:774-80.
38. K.R. Kutanzi, I. Koturbash, R.T. Bronson, I.P. Pogribny, O. Kovalchuk. Imbalance between apoptosis and cell proliferation during early stages of mammary gland carcinogenesis in ACI rats. Mutation Research, 694:1-6.
39. O. Kovalchuk, F. Zemp, J. Filkowski, A. Altamirano, J.S. Dickey, G. Jenkins-Baker, S. A. Marino, D.J. Brenner, W.M. Bonner, O.A. Sedelnikova. microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways. Carcinogenesis, 31:1882-8.
40. I.P. Pogribny, J. Filkowski, V.P. Tryndyak, S.I. Shpyleva and O. Kovalchuk. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. International Journal of Cancer, 127:1785-94.
41. K.R. Kutanzi, I. Koturbash, O. Kovalchuk. Reversibility of pre-malignant estrogen-induced epigenetic changes. Cell Cycle, 9:3078-84
42. J.Filkowski, Y. Ilnytsky, T. Bagnyukova, I. Koturbash, I. Pogribny and O. Kovalchuk. Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression. Carcinogenesis, 31:1110-5.
43. L.Luzhna and O.Kovalchuk. Modulation of DNA methylation levels sensitizes doxorubicin-resistant breast adenocarcinoma cells to radiation-induced apoptosis. Biochem Biophys Res Commun, 392: 113-7
2009
44. I. Koturbash, J. Thomas, O. Kovalchuk, I. Kovalchuk. Heat-killed bacteria induce genome instability in the gut and in distant spleen and liver tissues. Cell Cycle 8: 1935-9
45. S. Ilnytskyy, I. Koturbash and O. Kovalchuk. Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner. Environmental and Molecular Mutagenesis 50:105-13. EDITOR’S CHOICE PAPER.
2008
46. J. Tamminga, P. Kathiria, I. Koturbash, O. Kovalchuk. DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle 7:3731-3766. EDITOR’S CHOICE PAPER.
47. Y. Ilnytskyy, F.J. Zemp, I. Koturbash, O. Kovalchuk Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochem Biophys Res Commun. 377:41-45.
48. O. Kovalchuk, J. Filkowski, J. Meservy, Y.Ilnytskyy, V. Tryndyak, V. Chekhun and I. Pogribny. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Molecular Cancer Therapeutics 7: 2152-2159.
49. I. Koturbash, K. Kutanzi, R. Rodriguez-Juarez, D. Kogosov and O. Kovalchuk. Distinct epigenetic manifestations of the in vivo radiation-induced bystander effects in male and female mice. Mutation Research 642: 28-36.
50. I.Koturbash, F.J. Zemp, K. Kutanzi, L. Luzhna, J. Loree, B. Kolb and O. Kovalchuk. Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice. Cell Cycle 7: 1658-67.
51. J.Tamminga, I. Koturbash, M. Baker, K. Kutanzi, P. Kathiria, I. Pogribny, R. Sutherland and O. Kovalchuk. Paternal cranial exposure induces distant bystander damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle 7: 1238-45. COVER PAGE PICTURE.
52. C. Yauk, A. Polyzos, A. Rowan-Carroll, C.M. Somers, R.W. Godschalk, F J. Van Schooten, M.L. Berndt, I.P. Progribny, I. Koturbash, A. Williams, G.R. Douglas, O. Kovalchuk. Germline Mutations, DNA Damage and Global Hypermethylation in Mice Exposed to Particulate Air Pollution in an Urban/Industrial Location. Proceedings of the National Academy of Sciences of the USA 105:605-10
53. I. Koturbash, J. Loree, K. Kutanzi, C. Koganow, I. Pogribny, and O. Kovalchuk. In vivo bystander effect: cranial X-irradiation leads to elevated DNA damage and altered cellular proliferation and apoptosis in shielded spleen. International Journal of Radiation Oncology*Biology*Physics 70: 554-62.
54. O. Kovalchuk. Epigenetic research sheds new light on the nature of interactions between organisms and their environment. Environmental and Molecular Mutagenesis 49:1-3.
55. O. Kovalchuk, J.E. Baulch. Epigenetic changes and non-targeted radiation effects – is there a link? Environmental and Molecular Mutagenesis 49:16-25
56. C.L. Yauk, A.Polyzos, A.Rowan-Carroll, I. Kortubash, A. Williams, O. Kovalchuk. Tandem repeat mutation, global DNA methylation and regulation of DNA methyltransferases in cultured mouse embryonic stem cells chronically exposed to chemicals with different modes of action. Environmental and Molecular Mutagenesis 49:26-35.
2007
57. O. Kovalchuk, V. P. Tryndyak, B. Montgomery, A. Boyko, R. Rodriguez-Juarez, F.Zemp, A.R. Warbritton, J.R. Latendesse, I. P. Pogribny. Estrogen-induced rat breast carcinogenesis is characterized by alterations of DNA methylation, histone modifications and aberrant microRNAs expression. Cell Cycle 6: 2010-2018.
58. I. Pogribny, T.V. Bagnyukova, V.P. Tryndyak, L. Muskhelishvili, R. Rodriguez-Juarez, O. Kovalchuk, T. Han, J.C. Fuscoe, F.A. Beland. Gene expression profiling reveals the underlying molecular mechanisms of the early stages of tamoxifen-induced rat hepatocarcinogenesis. Toxicol Appl Pharmacol. 225:61-69.
59. Kovalchuk I, Molinier J, Yao Y, Arkhipov A, Kovalchuk O. Transcriptome analysis reveals fundamental differences in plant response to acute and chronic exposure to ionizing radiation. Mutation Research 624:101-13.
60. I. Koturbash, A. Boyko, R. Rodriguez-Juarez, R. McDonald, V. Tryndyak, I. Kovalchuk, I. Pogribny and O. Kovalchuk. Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo. Carcinogenesis 28, 1831-1838.
61. O. Sedelnikova, A. Nakamura, O. Kovalchuk, I. Koturbash, S. Mitchell, S. Marino, D. Brenner, W. Bonner DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Research 67, 4295-4302.
62. I. Pogribny, V. Tryndyak, A.Boyko, R. Rodriguez-Juarez, F.A. Beland and O. Kovalchuk. MicroRNAome deregulation in tamoxifen-induced rat liver carcinogenesis. Mutation Research 619, 30-37.
63. V. F. Chekhun, N. Y. Lukyanova, V.P. Tryndyak, O. Kovalchuk and I. P. Pogribny. Epigenetic profiling of multidrug resistant breast cancer cells reveals novel hypo- and hypermethylated targets. Molecular Cancer Therapeutics 6, 1089-1098.
64. Tryndyak VP, Kovalchuk O, Muskhelishvili L, Montgomery B, Rodriguez-Juarez R, Melnyk S, Ross SA, Beland FA, Pogribny IP. Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis. Molecular Carcinogenesis 46, 187-197.
2006
65. J. Loree, I. Koturbash, K. Kutanzi, M. Baker, I. Pogribny, and O. Kovalchuk. Radiation-induced DNA damage and epigenetic changes in rat mammary tissue: possible implications for radiation-induced carcinogenesis. International Journal of Radiation Biology 82, 805-815.
66. O. Kovalchuk, V. F. Chekhun and I. P. Pogribny. Role of microRNAome changes in drug resistance of breast cancer cells. Oncology, 11, 75.
67. I. Koturbash, M. Baker, J. Loree, K. Kutanzi, D. Hudson, I. Pogribny, O. Sedelnikova, W. Bonner and O. Kovalchuk. Epigenetic Dysregulation Underlies the Transgenerational Genome Instability in vivo. International Journal of Radiation Oncology*Biology*Physics 66, 327-330
68. V. P Tryndyak, O. Kovalchuk and I. P. Pogribny. Identification of differentially methylated sites within unmethylated DNA domains in normal and breast cancer cells. Analytical Biochemistry 356, 202-207.
69. V. P. Tryndyak, L. Muskhelishvili, O. Kovalchuk, R. Rodriguez-Juarez, B. Montgomery, S. A. Ross, M. I. Churchwell, F. A. Beland, I.P. Pogribny. Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis. Carcinogenesis 27, 1713-1720.
70. I. Koturbash, R.E. Rugo, C.A. Hendricks, J. Loree, B. Thibault, K. Kutanzi, I. Pogribny, J.C. Yanch, B.P. Engelward, and O. Kovalchuk. Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene 25, 4267-4275
71. V. Tryndyak, O. Kovalchuk, I. Pogribny. Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biology and Therapy 5, 65-70.
72. I. Koturbash, S. Cassie, M. Baker, Y. Ilnitsky, D. Hudson, E. Weber and O. Kovalchuk. Novel retinoblastoma binding protein RBBP9 modulates sex-specific radiation responses in vivo. Carcinogenesis 27, 465-474
2005
73. I. Pogribny, I. Koturbash, V. Tryndyak, D. Hudson, S.M. Stevenson, O. Sedelnikova, W. Bonner and O. Kovalchuk. Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus. Molecular Cancer Research 3, 553-561.
74. I. Koturbash, I. Pogribny, O. Kovalchuk. Stable loss of global DNA methylation in the radiation-target tissue-A possible mechanism contributing to radiation carcinogenesis? Biochem Biophys Res Commun. 337, 526-533.
75. J. Besplug, A. Ponton, J. Filkowski, I. Kovalchuk and O. Kovalchuk.. Sex differences in the low-dose radiation–induced oncogenic signaling. Int. J. Radiat. Biol. 81, 157-168.
76. I. Kovalchuk, V. Titov, B. Hohn and O. Kovalchuk (2005) Transcriptome profiling reveals similarities and differences in plant responses to cadmium and lead. Mutat Res. 570, 149-161
2004
77. G. Silasi, R. Diaz-Heijtz, J. Besplug, R. Rodriguez-Juarez, V. Titov, B. Kolb and O. Kovalchuk. Selective brain responses to acute and chronic low dose X-ray irradiation in males and females. Biochem Biophys Res Commun 325, 1223-1235.
78. J. Raiche, R. Rodriguez-Juarez, I. Pogribny and O. Kovalchuk. Sex and tissue specific expression of maintenance and de novo DNA methyltransferases upon low dose X-irradiation in mice. Biochem Biophys Res Commun 325, 39-47
79. O. Kovalchuk, C.A. Hendricks, S. Cassie, A.J. Engelward and B.P. Engelward. In vivo recombination after chronic damage exposure falls to below spontaneous levels in ‘Recombomice’. Molecular Cancer Research 2, 567-573.
80. I. Pogribny, J. Raiche, M. Slovack and O. Kovalchuk. Dose-dependence, sex- and tissue-specificity and persistence of radiation-induced genomic DNA methylation changes. Biochem Biophys Res Commun 320, 1253-1260
81. Kovalchuk O., Ponton A., Filkowski J and Kovalchuk I. Dissimilar genome response to acute and chronic low dose radiation in male and female mice. Mutation Research 550, 59-72.
82. Kovalchuk O., Burke P., Besplug J. Slovack M., Filkowski J.and Pogribny I. Methylation changes in muscle and liver tissues of male and female mice exposed to acute and chronic low dose X-ray-irradiation. Mutation Research 548, 75-84.
83. Kovalchuk, I., Pelczar, P. and Kovalchuk, O. The high frequency of nucleotide misincorporations upon the processing of the double-strand breaks. DNA repair 3, 217-223.
84. Kovalchuk I., Abramov V, Pogribny I and Kovalchuk O. Molecular aspects of plant adaptation to life in the Chernobyl zone. Plant Physiology 135, 357-363.
85. Besplug J., Filkowski J., Burke P., Kovalchuk I. and O. Kovalchuk. Atrazine induces homologous recombination but not point mutation in the transgenic plant-based biomonotoring assay. Archives of Environmental Contamination and Toxicology 46, 296-300.
86. Filkowski, J., Kovalchuk, O. and Kovalchuk, I. Genome stability of vtc1, tt4 and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. Plant Journal 38, 60-69.
87. Filkowski, J., Yeoman, A., Kovalchuk, O. and Kovalchuk, I. Systemic plant signal triggers genome instability. Plant Journal 38, 1-11.
2003
88. Kovalchuk O., Burke P., Arkhipov A., Kuchma N., James S. J., Kovalchuk I. and Pogribny I . Genome hypermethylation Pinus silvestris of Chernobyl – a mechanisms for radiation adaptation? Mutation Research 529, 13-20.
89. Kovalchuk O., Kovalchuk, I, Arkhipov A. , Hohn B. and Y. Dubrova. Extremely complex patterns of ionizing radiation-induced mutation in wheat microsatellite loci, Mutation Research 525, 93-101.
90. Kovalchuk, I., Kovalchuk, O., Kalck, V., Boyko, V., Filkowski, J., Heinlein, M. and Hohn, B. Pathogen induced systemic plant signal triggers DNA rearrangements. Nature 423, 760-762
91. Kovalchuk O., Telyuk P., Kovalchuk I., Kovalchuk L. and V. Titov. Plant bioassays for monitoring of the genotoxicity of drinking water from the inhabited areas of Ukraine affected by the Chernobyl accident. Bulletin of Environmental Contamination and Toxicology 70, 847-853.
92. Filkowski J., Besplug J., Burke P., Kovalchuk I. and O. Kovalchuk. Recombination- and point mutation-monitoring transgenic plants reveal the genotoxicity of commonly used herbicides 2,4-D and dicamba. Mutation Research, 542, 23-32.
93. Kovalchuk, I., Filkowski, J., Smith, K. and Kovalchuk, O. The dualistic nature of radicals: the high-low phenomenon. Plant Cell and Environment, 26, 1531-1539.
94. Kovalchuk I. and O. Kovalchuk. A New Use for Transgenic Plants – Environmental Biomonitors. Biotechnol Genet Eng Rev. 20, 23-45.
2002
95. Kovalchuk O., Hohn B., and I. Kovalchuk. Transgenic plants for environmental biomonitoring: new perspectives. K. Vasil (ed.) Plant Biotechnology 2002 and Beyond. Kluwer Academic Publishers, 479-483.
2001
96. Kovalchuk I. and Kovalchuk O. Biomonitoring with transgenic plants. ISB News Report. Covering Agricultural and Environmental Biotechnnology Developments, September, 1-4.
97. Kovalchuk, I., Kovalchuk, O. and B. Hohn. Biomonitoring of genotoxicity of environmental factors with transgenic plants. Trends Plant Sci. 6, 306-310.
98. Kovalchuk, O., Titov, V., Hohn, B. and I. Kovalchuk. A sensitive transgenic plant system to detect toxic inorganic compounds in the environment. Nature Biotechnology, 19, 568-572.
2000
99. Frisch, O., Hohn B., Kovalchuk, I. et Kovalchuk O. Des bio-indicateurs de pollution radioactive, Biofutur 205, 48-51.
100. Kovalchuk O., Arkhipov A., Dubrova Yu., Hohn B. and Kovalchuk I. Wheat mutation rate after Chernobyl Nature 407, 583-584.
101. Kovalchuk I., Kovalchuk O., Hohn B. Genome-wide variation of the somatic mutation frequency in transgenic plants EMBO J , 19, 4431-4438.
102. Kovalchuk O., Arkhipov A., Barylyak I., Karachov I., Titov V., Hohn B. and I. Kovalchuk.Plants experiencing chronic internal exposure to ionizing radiation exhibit higher frequency of homologous recombination than acutely irradiated plants. Mutation Research, 449, p.47-56.
1999
103. Kovalchuk, O.; Kovalchuk, I.; Titov, V.; Arkhipov, A. and Hohn, B. Radiation hazard caused by the Chernobyl accident in inhabited areas of Ukraine can be monitored by transgenic plants. Mutation Research 446, p.49-55.
104. Hohn B., Kovalchuk I., Kovalchuk O. Transgenic plants sense radioactive contamination. Bioworld, 6, p. 13-15.
105. Kovalchuk I., Kovalchuk O., Hohn B. Transgenic plants as bioindicators of environmental pollution. Review. AgBiotechNet, Vol. 1, October, ABN 030.
1998
Kovalchuk I., Kovalchuk O., Arkhipov A., and Hohn B. Transgenic Plants Are Sensitive Bioindicators of Nuclear Pollution Caused by the Chernobyl Accident. Nature Biotechnology, 16, p.1054-1057.
106. Kovalchuk O., Kovalchuk I., Arkhipov A., Telyuk P., Hohn B., and L. Kovalchuk. Allium cepa chromosome aberration test reliably measures genotoxicity of soils of inhabited areas of the Ukraine contaminated by the Chernobyl accident. Mutation Research, 415,1-2, p. 47-57.

Igor Kovalchuk:
2014

1. Sidler, C., Li, D., Kovalchuk, O., Kovalchuk, I. (2014) Development-dependent expression of DNA repair genes and epigenetic regulators in Arabidopsis plants exposed to ionizing radiation. Rad Res, in press.
2. Kovalchuk, I., Golubov, A., Koturbash, I., Kutanzi, K., Martin, O., Kovalchuk, O. (2014) Age-dependent changes in DNA repair in radiation-exposed mice. Rad Res (in press).
3. Sidler, C, Woycicki, R‎, Li, D; Wang, B‎; Kovalchuk, I‎; Kovalchuk, O (2014) Role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts. Aging, in press. IF:5.40
4. Sidler, C, Woycicki, R‎, Kovalchuk, I‎; Kovalchuk, O (2014) WI-38 senescence is associated with global and site-specific DNA hypomethylation. Aging, in press. IF:5.40
5. Jastrebova, O., Kovalchuk, I., Kovalchuk, L. (2014) Testing the mutagenicity of soils from different areas of the Ivano-Frankivsk region (Ukraine) using heterozygous Nicotiana tabacum (Su/+) plants. Carpath J Earth Env. in press. IF: 1.0
6. Migicovsky, Z., Kovalchuk, I. (2014) Transgenerational changes in plant physiology and in transposon expression in response to UV-C stress in Arabidopsis thaliana. Plant Signal Behav, in press.
7. Migicovsky, Z., Kovalchuk, I. (2014) Transgenerational inheritance of epigenetic response to cold in Arabidopsis thaliana. Biocat Agricul Biotech, in press.
8. Yao, Y, Robinson, AM, Zucchi, FCR, Robbins, JC, Babenko, O, Kovalchuk, O, Kovalchuk, I, Olson, DM and Metz, GAS (2014) Ancestral Exposure to Stress Epigenetically Programs Preterm Birth Risk and Adverse Maternal and Newborn Outcomes. BMC Medicine, in press. IF: 7.3
9. Zucchi FCR, Yao Y, Ilnytskyy Y, Robbins JC, Soltanpour N, Kovalchuk I, Kovalchuk O, Metz GA (2014) Lifetime Stress Cumulatively Programs Brain Transcriptome and Impedes Stroke Recovery: Benefit of Sensory Stimulation. PLoS ONE, in press. IF: 3.73
10. Kovalchuk I and Weselake, R. (2014) Trait introduction methods and innovation platforms in plant biotechnology. Editorial. Biocat Agricul Biotech, in press.
11. Migicovsky, Z., Yao, Y. and Kovalchuk, I. Transgenerational phenotypic and epigenetic changes in response to heat stress in Arabidopsis thaliana. Plant Signal Behav, in press.
12. Bilichak, A., Yao, Y., Titov, V., Golubov, A., Kovalchuk, I. (2014) Genome stability in the uvh6 mutant of Arabidopsis thaliana. Plant Cell Rep, in press. IF: 2.94
13. Kovalchuk, O., Walz, P. and Kovalchuk, I. (2014) Does bacterial infection cause genome instability and cancer in the host cell? Mutat Res, 761C:1-14.
14. Bilichak, A., Yao, Y. and Kovalchuk, I. (2014) Transient down-regulation of the RNA silencing machinery increases efficiency of Agrobacterium-mediated transformation of Arabidopsis. Plant Biotech J., in press. IF: 6.3
15. Bilichak, A. and Kovalchuk I. (2014) Manipulation of epigenetic factors and the DNA repair machinery for improving the frequency of plant transformation. Biocat Agricul Biotech, in press.
16. Maheshwari, P. and Kovalchuk, I. (2014) Genetic engineering of oilseed crops. Biocat Agricul Biotech, in press.
2013
17. Kovalchuk, I. (2013) Resisting transgenerational epigenetic reprogramming – examples and mechanisms of non-genetic inheritance. Non-Genetic Inheritance, 1, 51-61.
18. Sidler C, Woycicki R, Ilnytskyy Y, Metz G, Kovalchuk I, Kovalchuk O. (2013) Immunosenescence Is Associated With Altered Gene Expression And Epigenetic Regulation In Primary And Secondary Immune Organs. Front Genet, 4, 211, doi: 10.3389/fgene.2013.00211.
19. Kovalchuk, I., Walz, P., Thomas, J. and Kovalchuk, O. (2013) Genomic instability in liver cells caused by an LPS-induced bystander-like effect. PLoS ONE, 8(7):e67342. IF: 3.73
20. Alam, M., Kovalchuk, I. (2013) Epigenetic response to changes in diets and in response to toxic compounds. Galician Medical Journal, 20(2), 16-20.
21. Kathiria, P., Sidler, C., Woycicki, R., Yao, Y. and Kovalchuk, I. (2013) Effect of External and Internal Factors on the Expression of Reporter Genes Driven by the N Resistance Gene Promoter. Plant Signal Behav, 8(7). doi:pii: e24760. IF:2.0
22. Kovalchuk, I., Walz, P., Thomas, J. and Kovalchuk, O. (2013) The increased expression of proteins involved in proliferation, DNA repair and DNA methylation in spleen of mice exposed to E. coli O157:H7 lipopolysaccharide. Environ Mol Mutagen, 54(6):421-8. IF: 3.7
23. Rahavi Reza, SM and Kovalchuk I. (2013) Transgenerational changes in Arabidopsis thaliana in response to UV-C, heat and cold. Biocat Agricul Biotech, 2(3), 226-233.
24. Rahavi Reza, SM and Kovalchuk I. (2013) Changes in homologous recombination frequency in Arabidopsis thaliana plants exposed to stress depend on time of exposure during development and on duration of stress exposure. Physiol Mol Biol Plant, 10.1007/s12298-013-0197-z.
25. Yao, Y., Kathiria, P., Kovalchuk, I. (2013) A systemic increase in the recombination frequency upon local infection of Arabidopsis thaliana plants with oilseed rape mosaic virus depends on plant age, the initial inoculum concentration and the time for virus replication. Front. Plant Phys. 4:61.
26. Yao Y, Bilichak A, Titov V, Golubov A, Kovalchuk I. (2013) Genome stability of Arabidopsis atm, ku80 and rad51b mutants: somatic and transgenerational responses to stress. Plant Cell Physiol, 54(6):982-9. IF: 4.7
27. Zucchi, FCR, Yao, Y, Ward, ID, Ilnytsky, Y, Olson, DM, Benzies, K, Kovalchuk, I, Kovalchuk, O, Metz, GA. (2013) Maternal Stress Induces Epigenetic Signatures of Psychiatric and Neurological Diseases in the Offspring. PLoS ONE, 8(2):e56967. IF: 3.73
28. Migicovsky, Z., Kovalchuk, I. (2013) Changes to DNA methylation and homologous recombination frequency in the progeny of stressed plants. Biochem Cell Biol, 91(1):1-5. IF: 2.7.
29. Shim, Y-S., Eudes, F., Kovalchuk, I. (2013) dsDNA and protein co-delivery in triticale microspores. In Vitro Cell Dev Biol Plant. IF: 1.5
30. Maheshwari, P., and Kovalchuk, I. (2013) Combination of ammonium nitrate, cerium chloride and potassium chloride salts improves Agrobacterium tumefaciens-mediated transformation of Nicotiana tabacum. Plant Biotech Rep, 7 (2), 147-154. IF: 1.2.
2012
31. Kovalchuk, I. (2012) Transgenerational epigenetic inheritance in animals. Front. Gene., 3:76. doi: 10.3389/fgene.2012.00076.
32. Yao, Y., Bilichak, A., Golubov, A., Kovalchuk, I. (2012) ddm1 plants are sensitive to methyl methane sulfonate and NaCl stresses and are deficient in DNA repair. Plant Cell Reports, 31(9):1549-61. IF: 2.74.
33. Zemp, F., Sidler, C., Kovalchuk, I. (2012) Increase in recombination rate in Arabidopsis thaliana plants sharing gaseous environment with X-ray and UVC-irradiated plants depends on production of radicals. Plant Signal Behavior, 7(7):782-7. IF: 2.0
34. Yao, Y., Danna, C.H., Ausubel, F.M., Kovalchuk, I. (2012) Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants. Plant Signal Behavior, 7(7):741-5. IF: 2.0
35. Ziemienowicz, A., Shim, Y-S, Matsuoka, A., Eudes, F. and Kovalchuk, I. (2012) A novel method of transgene delivery into Triticale plants using the Agrobacterium T-DNA-derived nano-complex. Plant Physiology, 158(4):1503-13. IF: 7.0
36. Bilichak, A., Ilnystkyy, Y., Hollunder, J., Kovalchuk, I. (2012) The progeny of Arabidopsis thaliana plants exposed to salt exhibit changes in DNA methylation, histone modifications and gene expression. PLoS ONE, 7(1): e30515. IF: 4.4
37. Babenko, O., Golubov, A., Ilnytsky, Y., Kovalchuk, I., Metz, GA. (2012) Genomic and Epigenomic Responses to Chronic Stress Involve miRNA-mediated Programming. PLoS ONE, 7(1): e29441. IF: 4.4
38. Babenko, O., Kovalchuk, I., Metz, GA. (2012) Epigenetic Programming of Neurodegenerative Diseases by Adverse Environment. Brain Research, 1444:96-111. IF: 2.62
39. Mandal, R., Kathiria, P., Psychogios, N., Bouatra, S., Krishnamurthy, R., Wishart, D., Kovalchuk, I. (2012) Progeny of tobacco mosaic virus-infected Nicotiana tabacum plants exhibit trans-generational changes in metabolic profiles. Biocatalysis Agricultural Biotechnology, 2:115-123.
40. Migicovsky, Z. and Kovalchuk, I. (2012) Epigenetic modifications during angiosperm gametogenesis. Front. Plant Sci. 3:20. doi: 10.3389/fpls.2012.00020 IF: 3.7
2011
41. Yao, Y., Danna, CH, Zemp, FJ, Titov, V, Ciftci, O, Przybylski, R, Ausubel, FM, Kovalchuk, I. (2011) UV-C irradiated plants emit volatiles that trigger genomic instability in neighboring plants. Plant Cell, 23(10):3842-52. IF: 10.65
42. Reza Rahavi, M., Migicovsky, Z. and Kovalchuk, I. (2011) Transgenerational adaptation to heavy metal salts in Arabidopsis. Front. Plant Sci. 2:91. IF: 3.7
43. Hudson, D., Kovalchuk, I., Koturbash, I., Kolb, B., Martin, O.A., Kovalchuk, O. (2011) Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals. Aging, 3(6):609-20. IF: 5.4
44. Maheshwari P, Selvaraj G, Kovalchuk I. (2011) Optimization of Brassica napus (canola) explant regeneration for genetic transformation. N Biotechnol. 29(1):144-55. IF: 2.87
45. Migicovsky, Z. and Kovalchuk, I. (2011) Epigenetic memory in mammals. Front. Gene. 2:28. doi: 10.3389/fgene.2011.00028
46. Golubov, A., Maheshwari, P., Bilichak, A., Kovalchuk, I. (2011) New in vitro DNA polymerase activity and fidelity assay reveals age-dependent changes in Arabidopsis thaliana. International Journal Plant Biology, 2(1), DOI: 10.4081/pb.2011.e7.
47. Maheshwari, P. and Kovalchuk, I. (2011) Efficient shoot regeneration from internodal explants of Populus angustifolia, Populus balsamifera and Populus deltoids N Biotechnol., 28(6):778-87. IF: 2.87
48. Boyko, A. and Kovalchuk, I. (2011) Genome instability and epigenetic modification – heritable responses to stress. Curr Opin Plant Biol, 14(3):260-6. IF: 9.43
49. Boyko, A. and Kovalchuk, I. (2011) Genetic and epigenetic effects of plant-pathogen interactions – an evolutionary perspective. Molecular Plant, 4(6):1014-23. IF: 6.6
50. Yao, Y., Golubov, A., Bilichak, A. and Kovalchuk, I. (2011) Local infection with oilseed rape mosaic virus promotes genetic rearrangements in systemic Arabidopsis tissue. Mutat Res. 709-710:7-14. IF:3.90
51. Yao, Y. and Kovalchuk, I. (2011) Abiotic stress leads to somatic and heritable changes in homologous recombination frequency, point mutation frequency and microsatellite stability in Arabidopsis plants. Mutat Res. 707(1-2):61-6. IF: 3.90
52. Ziemienowicz, A., Rahavi, S.M.R. and Kovalchuk, I. (2011) Stimulatory effect of CaCl2, NaCl and NH4NO3 salts on ssDNA binding activity of RecA depends on nucleotide cofactor and buffer pH. BMB Reports, 44(5): 341-346. IF:2.17
53. Boyko A, Matsuoka A, Kovalchuk I. (2011) Potassium chloride and rare earth elements improve plant growth and increase the frequency of the Agrobacterium tumefaciens-mediated plant transformation. Plant Cell Rep. 30:505–518. IF:2.28
54. Jastrebova, O., Kovalchuk, I., Kovalchuk, L. (2011) Analysis of soil genotoxicity in the city of Ivano-Frankivsk using Nicotiana tabacum Su/+ plants. Carpath J Earth Env. 6(2), pp.
2010
55. Yao, Y, Bilichak, A, Golubov, A, Blevins, T, Kovalchuk, I (2010) Differential sensitivity of Arabidopsis siRNA biogenesis mutants to genotoxic stress. Plant Cell Rep., 29(12): 1401-10. IF:2.28
56. Golubov A, Yao Y, Maheshwari P, Bilichak A, Boyko A, Belzile F, Kovalchuk I. (2010) Microsatellite instability in Arabidopsis thaliana increases with plant development. Plant Physiol. 154(3):1415-27. IF: 7.01
57. Kathiria P, Golubov A, Sidler C, Kalischuk M, Kawchuk LM, Kovalchuk I. (2010) Tobacco mosaic virus infection results in an increase in recombination frequency and resistance to viral, bacterial and fungal pathogens in the progeny of infected tobacco plants. Plant Physiol. 153(4): 1859-70. IF: 7.01
58. Boyko A, Blevins T, Yao Y, Golubov A, Bilichak A, Ilnytskyy Y, Hollander J, Meins F, Kovalchuk I. (2010) Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of dicer-like proteins. PLoS One. 5(3):e9514. IF: 4.41
59. Boyko A and Kovalchuk I. (2010) Transgenerational response to stress in Arabidopsis thaliana. Plant Signaling Behavior, Aug 27th, 5(8), 995-998. IF: 2.0
60. Boyko A, Golubov A, Bilichak A, Kovalchuk I. (2010) Chlorine Ions but not Sodium Ions Alter Genome Stability of Arabidopsis Thaliana. Plant Cell Physiol. 51(6):1066-78. IF: 4.7
61. Kathiria P, Kovalchuk I. (2010) Reporter gene-based recombination lines for studies of genome stability. Methods Mol Biol. 2010;631:243-52.
62. Boyko A, Kovalchuk I. (2010) Detection and Quantification of DNA Strand Breaks Using the ROPS (Random Oligonucleotide Primed Synthesis) Assay. Methods Mol Biol. 631:237-42.
63. Boyko A, Kovalchuk I. (2010) Analysis of mutation/rearrangement frequencies and methylation patterns at a given DNA locus using restriction fragment length polymorphism. Methods Mol Biol. 631:49-62.
64. Kathiria P, Kovalchuk I. (2010) In situ analysis of DNA methylation in plants. Methods Mol Biol. 631:41-8.
65. Boyko A, Kovalchuk I. (2010) Detection of changes in global genome methylation using the Cytosine-extension assay. Methods Mol Biol. 631:33-9.
66. Boyko A, Kovalchuk I. (2010) Analysis of Locus-Specific Changes in Methylation Patterns Using a COBRA (Combined Bisulfite Restriction Analysis) Assay. Methods Mol Biol. 631:23-31.
67. Boyko, A., Molinier, J., Chatter, W., Laroche, A., Kovalchuk, I. (2010) Acute but not chronic exposure to abiotic stress results in transient reduction of expression levels of the transgene driven by the 35S promoter. New Biotechnology, 27(1):70-77. IF: 2.87
2009
68. Koturbash I, Thomas, J, Kovalchuk O, Kovalchuk, I. (2009) Heat-killed bacteria induce genome instability mouse small intestine, liver and spleen tissues. Cell Cycle, 8(12):1935-9. IF:5.25
69. Boyko A., Matsuoka, A., Kovalchuk, I. (2009) High frequency Agrobacterium tumefaciencs-mediated plant transformations induced by ammonium nitrate. Plant Cell Reports, 28(5):737-57. IF:2.28
70. Greer, M.S., Eudes, F., Kovalchuk, I. (2009) Effects of Ammonium Nitrate upon Direct Somatic Embryogenesis and Biolistic Transformation of Wheat. New Biotechnol, 26(1-2), 44-52. IF: 2.87
2008
71. Kovalchuk, I. and Kovalchuk, O. (2008) Transgenic Plants as Environmental Biosensors. In Special Issue “Phytosensors: Environmental Sensing with Plants and Plant Cells”. Sensors, 8, 1539-1558. Review. IF:1.92
72. Boyko A., Kovalchuk, I. (2008) Epigenetics of plant response to stress. Environ Mol Mutagen, 49(1):61-72, Review. IF:3.49
2007
73. Kovalchuk, O., V. P. Tryndyak, B. Montgomery, A. Boyko, R. Rodriguez-Juarez, F. Zemp, I. Kovalchuk, A.R. Warbritton, J.R. Latendesse, I. P. Pogribny. (2007) Estrogen-induced rat breast carcinogenesis is characterized by alterations of DNA methylation, histone modifications and aberrant microRNAs expression. Cell Cycle, 6(16), 2010-2018. IF:5.24
74. Kovalchuk, I., Molinier, J., Yao, Y., Kovalchuk, O. (2007) Transcriptome analysis reveals fundamental differences in plant response to acute and chronic exposure to ionizing radiation. Mutation Research, 624(1-2):101-13. IF: 3.90
75. Koturbash I, Boyko A, Rodriguez-Juarez R, McDonald R, Tryndyak V, Kovalchuk I, Pogribny I, Kovalchuk O. (2007) Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo. Carcinogenesis, 28(8):1831-8. IF:5.65
76. Boyko A., Kovalchuk I. (2007) Genetics and epigenetics of pathogen-induced genome instability. Plant Stress, Review, 1(1), 23-31.
77. Boyko, A., Kathiria, P., Zemp, F., Yao, Y., Pogribny, I., Kovalchuk, I. (2007) Transgenerational changes in the genome stability and methylation in pathogen-infected plants. Nucleic Acids Research, 35(5):1714-25. Profiled in “Faculty of 1000” with the factor of “6.0” IF: 7.84
2006
78. Boyko, A. Greer, M. and Kovalchuk, I. (2006) Acute exposure to UVB has more pronounced effect on plant genome stability than chronic exposure. Mutation Research, 602, 100-109. IF: 3.90
79. Boyko, A., Hudson, D., Bhomkar, P., Kathiria, P. Kovalchuk, I. (2006) Increase of homologous recombination frequency in vascular tissue of Arabidopsis plants exposed to salt stress. Plant Cell Physiology, 47(6):736-42. IF: 4.7
80. Boyko, A., Filkowski, J., Kovalchuk, I. (2006) Double strand break repair in plants is developmentally regulated. Plant Physiology, 141, 1-10. IF: 7.01
81. Boyko, A., Filkowski, J., Hudson, D., Kovalchuk, I. (2006) Homologous recombination in plants is organ specific. Mutation Research, 595, 145-155. IF: 3.90
2005
82. Boyko A., Filkowski J. and Kovalchuk I (2005) Homologous recombination in plants is temperature and day length dependent. Mutation Research, 572, 73-83. IF: 3.90
83. Besplug, J., Filkowski J., Kovalchuk, I., Kovalchuk, O. (2005) Sex- and tissue-specific differences in the low-dose radiation-induced oncogenic signaling. International Journal Radiation Biology, 81, 157-68. IF: 1.84
84. Ilnytskyy, Y., Yao, Y. and Kovalchuk, I. (2005) Double-strand break repair machinery is sensitive to UV radiation. Journal Molecular Biology, 345, 707-715. IF: 4.1
85. Molinier, J., Oakeley, E.J., Niederhauser, O., Kovalchuk, I. Hohn, B. (2005) Dynamic response of plant genome to ultraviolet radiation and other genotoxic stresses Mutation Research, 571, 235-47. IF: 3.90
86. Kovalchuk, I., Titov, V., Hohn, B. Kovalchuk, O. (2005) Transcriptome profiling reveals similarities and differences in plant responses to cadmium and lead. Mutation Research, 579, 149-161. IF: 3.90
2004
87. Dube, T., Kovalchuk, I., Hohn, B. and Thomson, JA. (2004) Agrobacterium tumefaciens Mediated Transformation of Plants by the pTF-FC2 plasmid is Efficient and Strictly Dependent on the MobA Protein. Plant Molecular Biology, 55, 531-539. IF: 4.15
88. Filkowski, J., Yeoman, A., Kovalchuk, O. and Kovalchuk, I. (2004) Systemic plant signal triggers genome instability. Plant J., 38, 1-11. IF: 6.95
89. Kovalchuk, I., Abramov, V., Pogribny, I. and Kovalchuk, O. (2004) Molecular aspects of plant adaptation to life in the Chernobyl zone. Plant Physiology, 135(1), 357-63. IF: 7.01
90. Filkowski, J., Kovalchuk, O., Kovalchuk, I. (2004) Genome stability of vtc1, tt4 and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. Plant J., 38, 60-69. IF: 6.95
91. Ilnytskyy, Y., Boyko, A. and Kovalchuk, I. (2004) Luciferase-based transgenic recombination assay is more sensitive than -glucoronidase-based. Mutation Research, 559, 189-97. IF: 3.90
92. Kovalchuk O., Ponton A., Filkowski, J and Kovalchuk I. (2004) Dissimilar genome response to acute and chronic low-dose radiation in male and female mice. Mutation Research, 550, 59-72. IF: 3.90
93. Kovalchuk, I., Pelczar P. and O. Kovalchuk. (2004) The high frequency of nucleotide misincorporations upon the processing of the double-strand breaks. DNA Repair, 3, 217-223. IF: 4.30
94. Besplug J., Filkowski J., Burke P., Kovalchuk I. and O. Kovalchuk. (2004) Atrazine induces homologous recombination but not point mutation in the transgenic plant-based biomonotoring assay. Arch. Environ. Cont. Toxic. 46(3), 296-300. IF: 1.93
95. Filkowski, J., Kovalchuk, O. and Kovalchuk, I. (2004) Dissimilar mutation and recombination rates in Arabidopsis and tobacco. Plant Science, 166, 265-272. IF: 2.56
2003
96. Kovalchuk I., Bojko V., Kovalchuk O., Gloeckler V., Filkowski, J., Heinlein, M. and B. Hohn. (2003) Pathogen induced systemic plant signal triggers genome instability. Nature, 423, 760-762. Profiled in “Faculty of 1000” with the factor of “9.2” IF: 31.43
97. P. Pelczar, V. Glockler and I. Kovalchuk. (2003) Human and tobacco: organisms with similar genomes size but different genome maintenance strategy. Journal Molecular Biology, 331, 771-9. IF: 4.1
98. Kovalchuk O., Burke P., Arkhipov A., Kuchma N., James S.J., Kovalchuk I. and Pogribny I (2003) Genome hypermethylation in Chernobyl pine – a mechanisms for radiation adaptation? Mutation Research, 529, 13-20. IF: 3.90
99. Filkowski J., Besplug J., Burke P., Kovalchuk I. and O. Kovalchuk (2003) Recombination- and point mutation-monitoring transgenic plants reveal the genotoxicity of commonly used herbicides 2,4-D and dicamba. Mutation Research, 542(1-2), 23-32. IF: 3.90
100. Kovalchuk, I., Filkowski, J., Smith, K. and Kovalchuk, O. (2003) The dualistic nature of radicals: the high-low phenomenon. Plant Cell Environment, 26, 1531-1539. IF: 5.15
101. Kovalchuk, I. Kovalchuk, A. Arkhipov, B. Hohn and Yu. Dubrova. (2003) Extremely complex pattern of microsatellite mutation in the germline of wheat exposed to the post-Chernobyl radioactive contamination. Mutation Research, 525, 93-101. IF: 3.90
102. Kovalchuk, I. Kovalchuk, P. Telyuk, B. Hohn, V. Titov, L. (2003) Kovalchuk. Monitoring of the genotoxicity of drinking water from the inhabited areas of Ukraine affected by the Chernobyl accident using plant bioassays. Bulletin Environmental Contamination Toxicology, 70, 847-853. IF: 1.14
103. Kovalchuk, I. and Kovalchuk O. (2003) A New Use for Transgenic Plants – Environmental Biomonitors. Biotechnology Genetic Engineering Reviews, Annual Review, 20, ch. 2.
2002
104. Li, A., Schurmann, D., Gallego, F., Kovalchuk, I., B. Tinland (2002) Repair of damaged DNA by Arabidopsis cell extract. Plant Cell, 14, 263-273. IF: 10.65
2001
105. Kovalchuk, O., Titov, V., Hohn, B. and I. Kovalchuk (2001) A sensitive transgenic plant system to detect toxic inorganic compounds in the environment. Nature Biotechnology, 19, 568-572. IF: 31.1
106. Kovalchuk, I., Kovalchuk, O. and B. Hohn (2001) Biomonitoring of genotoxicity of environmental factors with transgenic plants. Trends in Plant Scince, Review, 6, 306-310. IF: 10.73
107. Kovalchuk, I. and Kovalchuk O. (2001) Bioindication with transgenic plants. ISB News Rep. Review, Sep., 1-3.
2000
108. Kovalchuk O., Arkhipov A., Dubrova Yu., Hohn B. and Kovalchuk I. Wheat mutation rate after Chernobyl (2000) Nature 407, 583-584. IF: 31.43
109. Kovalchuk I., Kovalchuk O., Hohn B. Genome-wide variation of the somatic mutation frequency in transgenic plants (2000) EMBO J., 19, 4431-4438.
110. Kovalchuk O., Arkhipov A., Barylyak I., Karachov I., Titov, V., Hohn B. and I. Kovalchuk (2000) Plants experiencing chronic internal exposure to ionizing radiation exhibit higher frequency of homologous recombination than acutely irradiated plants. Mutation Research, 449, p.47-56. IF: 3.90
111. Gorbunova, V., Avivi-Ragolski, N., Shalev, G., Kovalchuk, I., Abbo, S., Hohn, B. and Levy, A. (2000) A new hyperrecombinagenic mutant of Nicotiana tabacum. Plant J. 24, 601-611. IF: 6.95
112. Kovalchuk, I., Kovalchuk, O., Fritsch, O., Hohn, B. (2000) Des bio-indicators de pollution radioactive, Biofutur, 205, 48-51.
1999
113. Kovalchuk, O.; Kovalchuk, I., Titov, V.; Arkhipov, A. and Hohn, B. (1999) Radiation hazard caused by the Chernobyl accident in inhabited areas of Ukraine can be monitored by transgenic plants. Mutation Research 446, p.49-55. IF: 3.90
114. Hohn B., Kovalchuk I., Kovalchuk O. (1999) Transgenic plants sense radioactive contamination. Bioworld, 6, p. 13-15.
115. Kovalchuk I., Kovalchuk O., Hohn B. (1999) Transgenic plants as bioindicators of environmental pollution. Review. AgBiotechNet, Vol. 1, October, ABN 030.
1998
116. Kovalchuk I, Kovalchuk O, Arkhipov A, Hohn B. (1998) Transgenic plants are sensitive bioindicators of nuclear pollution caused by the Chernobyl accident. Nat Biotechnol. 16, 1054-9. IF: 31.1
117. Kovalchuk O, Kovalchuk I, Arkhipov A, Telyuk P, Hohn B, Kovalchuk L. (1998) The Allium cepa chromosome aberration test reliably measures genotoxicity of soils of inhabited areas in the Ukraine contaminated by the Chernobyl accident. Mutat Res. 415(1-2), 47-57. IF: 3.90